JAM3 and PICK1

Number of citations of the paper that reports this interaction (PubMedID 15811349)
11

Data Source:
HPRD (in vivo)

		JAM3	PICK1
Description		junctional adhesion molecule 3	protein interacting with PRKCA 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Microvillus Cell-cell Junction Bicellular Tight Junction Desmosome Filamentous Actin Paranodal Junction Schmidt-Lanterman Incisure Cell-cell Contact Zone Tight Junction Protein Complex Involved In Cell Adhesion	Cytoplasm Mitochondrion Golgi Apparatus Cytosol Cytoskeleton Plasma Membrane Synaptic Vesicle Postsynaptic Density Aggresome Cell Junction Endocytic Vesicle Membrane Trans-Golgi Network Membrane Presynaptic Membrane Neuron Projection Synapse Perinuclear Region Of Cytoplasm Postsynaptic Early Endosome
	Molecular Function	Integrin Binding Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell-cell Adhesion Mediator Activity	G Protein-coupled Receptor Binding Protein Kinase C Binding Signaling Receptor Binding Protein Binding Phospholipid Binding Protein C-terminus Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Metal Ion Binding Actin Filament Binding Arp2/3 Complex Binding Membrane Curvature Sensor Activity
	Biological Process	Angiogenesis Neutrophil Homeostasis Adaptive Immune Response Myeloid Progenitor Cell Differentiation Leukocyte Migration Involved In Inflammatory Response Cell-matrix Adhesion Spermatid Development Transmission Of Nerve Impulse Establishment Of Cell Polarity Extracellular Matrix Organization Axon Regeneration Negative Regulation Of Integrin Activation Negative Regulation Of Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Adherens Junction Assembly Protein Localization To Cell Surface Myelination Apical Protein Localization Leukocyte Migration Regulation Of Neutrophil Chemotaxis Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion Hematopoietic Stem Cell Migration To Bone Marrow Granulocyte Migration Cell-cell Adhesion Protein Localization To Cell Junction	Positive Regulation Of Receptor Internalization Protein Phosphorylation Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Monoamine Transport Glial Cell Development Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Response To Decreased Oxygen Levels Cellular Response To Glucose Starvation DNA Methylation Involved In Embryo Development DNA Methylation Involved In Gamete Generation Receptor Clustering Neuronal Ion Channel Clustering Regulation Of Insulin Secretion Long-term Synaptic Depression Dendritic Spine Organization Dendritic Spine Maintenance
Pathways		Cell surface interactions at the vascular wall Integrin cell surface interactions	Cell surface interactions at the vascular wall Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Body fat percentage ( 26833246)
Interacting Genes		7 interacting genes: F2RL2 ITGAM ITGAX JAM2 PICK1 RHOU TJP1	47 interacting genes: AFDN AKT1 APTX AQP1 ARF1 ARF3 ASIC1 ASIC2 ATXN1L ATXN3 ATXN7 ATXN7L3 BTG2 CIC COIL CTNNB1 EFNB1 EFNB2 EHD2 EPHB2 ERBB2 ERBIN F11R FXN GFI1 GFI1B GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIP1 GRM3 GRM7 JAM3 LRP2BP NECTIN2 NECTIN4 PRKCA PRKCG PRKN PRLHR SACS SLC6A3 UBQLN4 USP7
Entrez ID		83700	9463
HPRD ID		06042	16176
Ensembl ID		ENSG00000166086	ENSG00000100151
Uniprot IDs		Q9BX67	A0A024R1J5 Q9NRD5
PDB IDs			2GZV 6AR4 6BJN 6BJO
Enriched GO Terms of Interacting Partners?
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