ZMIZ2 and TRAPPC6A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZMIZ2	TRAPPC6A
Description		zinc finger MIZ-type containing 2	trafficking protein particle complex 6A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Nuclear Replication Fork	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	RNA Polymerase II Transcription Factor Binding Transcription Coregulator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity SUMO Ligase Activity	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway Protein Sumoylation Positive Regulation Of Transcription By RNA Polymerase II Chromatin-mediated Maintenance Of Transcription SMAD Protein Signal Transduction	ER To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly
Pathways			COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs			S-PALMITOYL-L-CYSTEINE
Diseases
GWAS		General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 27863252) Red blood cell count ( 27863252)	Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		21 interacting genes: AR ARSJ ASB13 BANP C2orf88 CRCP INTS4 LRRC37A11P MCPH1 MVP NBL1 PIAS3 PIN1 RANBP3 SALL2 SCAMP1 SELENOV SOCS6 SSX2 TP53 TRAPPC6A	15 interacting genes: CRYAB EFS HOXA1 IKZF3 RAB3IP RAD54B TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B ZMIZ2 ZNRD2
Entrez ID		83637	79090
HPRD ID		13225	14503
Ensembl ID		ENSG00000122515	ENSG00000007255
Uniprot IDs		E7EWM3 Q8NF64	B7TZ90 O75865
PDB IDs			2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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