CASP2 and GOLGA3

Number of citations of the paper that reports this interaction (PubMedID 10791974)
97

Data Source:
HPRD (in vivo, in vitro)

		CASP2	GOLGA3
Description		caspase 2	golgin A3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Membrane	Golgi Membrane Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Membrane Golgi Transport Complex Golgi Cisterna Membrane Extrinsic Component Of Golgi Membrane
	Molecular Function	Cysteine-type Endopeptidase Activity Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis	Protein Binding Cadherin Binding
	Biological Process	Luteolysis Neural Retina Development Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Brain Development Aging Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Processing Ectopic Germ Cell Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Cellular Response To Mechanical Stimulus Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Execution Phase Of Apoptosis Positive Regulation Of Apoptotic Signaling Pathway	Intra-Golgi Vesicle-mediated Transport Spermatogenesis
Pathways		NOD1/2 Signaling Pathway NADE modulates death signalling TP53 Regulates Transcription of Caspase Activators and Caspases
Drugs
Diseases
GWAS			Basal metabolic rate ( 31453325) Basal metabolic rate variance ( 31453325) Body mass index ( 28552196) Immune response to smallpox vaccine (IL-6) ( 22542470)
Interacting Genes		29 interacting genes: ADCYAP1 BID CASP10 CASP14 CASP3 CASP7 CASP8 CCND3 CFLAR CRADD CSNK2A1 DCTN1 DSP EEF1A1 GOLGA3 GRB2 KPNA2 MDM2 MZB1 NLRP1 NOD1 NOL3 PIDD1 RAI1 RB1 RPL30 RXRA SUMO1 UBE2I	14 interacting genes: ATXN7 CASP2 CASP3 CASP7 DEAF1 GOLGA7 GOPC KCNJ1 MPI PXMP2 TCF7 TSNAX ZNF10 ZNF26
Entrez ID		835	2802
HPRD ID		02800	03990
Ensembl ID		ENSG00000106144	ENSG00000090615
Uniprot IDs		A0A087WYM1 A0A0S2Z3H1 D3DXD9 P42575	Q08378
PDB IDs		1PYO 2P2C 3R5J 3R6G 3R6L 3R7B 3R7N 3R7S 3RJM 6GKF 6GKG
Enriched GO Terms of Interacting Partners?
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