TRRAP and BRD8

Number of citations of the paper that reports this interaction (PubMedID 26496610)
285

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		TRRAP	BRD8
Description		transformation/transcription domain associated protein	bromodomain containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	SAGA Complex PCAF Complex Swr1 Complex Nucleus Nucleoplasm Golgi Apparatus STAGA Complex Transcription Factor TFTC Complex NuA4 Histone Acetyltransferase Complex	Swr1 Complex Nucleus Nucleoplasm Mitochondrion NuA4 Histone Acetyltransferase Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding	DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding
	Biological Process	DNA Repair Regulation Of Transcription, DNA-templated Histone Acetylation Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Histone H2A Acetylation Beta-catenin-TCF Complex Assembly	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Signal Transduction Cell Surface Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex HATs acetylate histones Ub-specific processing proteases	HATs acetylate histones
Drugs
Diseases
GWAS		Mean corpuscular volume ( 27863252)	Autism spectrum disorder or schizophrenia ( 28540026) Menarche (age at onset) ( 25231870)
Interacting Genes		17 interacting genes: ACTL6A ATXN7 AURKA BRCA1 BRD8 CTNNB1 E2F1 E2F4 EP400 ESR1 KAT2A MAX MRGBP MYC PYGO2 SKP1 TCF3	8 interacting genes: FSD2 MIS18A MRGBP PPARG RXRA THRB TRRAP WEE1
Entrez ID		8295	10902
HPRD ID		04310	04166
Ensembl ID		ENSG00000196367	ENSG00000112983
Uniprot IDs		Q9Y4A5	B4DEG9 B4DMS9 B4DN43 Q9H0E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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