COLQ and BCHE

Number of citations of the paper that reports this interaction (PubMedID 10529218)
13

Data Source:
HPRD (in vitro)

		COLQ	BCHE
Description		collagen like tail subunit of asymmetric acetylcholinesterase	butyrylcholinesterase
Image
GO Annotations	Cellular Component	Collagen Trimer Basement Membrane Extracellular Space Plasma Membrane Cell Junction Extracellular Matrix Neuromuscular Junction Synaptic Cleft Collagen-containing Extracellular Matrix	Extracellular Region Nuclear Envelope Lumen Endoplasmic Reticulum Lumen Membrane Blood Microparticle
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Heparin Binding	Amyloid-beta Binding Catalytic Activity Acetylcholinesterase Activity Cholinesterase Activity Enzyme Binding Choline Binding Identical Protein Binding
	Biological Process	Acetylcholine Catabolic Process In Synaptic Cleft Regulation Of Synaptic Growth At Neuromuscular Junction Extracellular Matrix Organization Skeletal Muscle Acetylcholine-gated Channel Clustering Establishment Of Protein Localization To Membrane	Learning Negative Regulation Of Cell Proliferation Neuroblast Differentiation Choline Metabolic Process Response To Alkaloid Cocaine Metabolic Process Negative Regulation Of Synaptic Transmission Response To Glucocorticoid Response To Folic Acid
Pathways			Neurotransmitter clearance Synthesis of PC Synthesis, secretion, and deacylation of Ghrelin
Drugs			Choline Tacrine Dipivefrin Pyridostigmine Galantamine Isoflurophate Pralidoxime Malathion Ranitidine Hexafluronium Demecarium Rivastigmine Edrophonium Echothiophate Mivacurium Diethylphosphono Group Methylphosphinic Acid Butyric Acid 9-N-Phenylmethylamino-Tacrine 2-(N-Morpholino)-Ethanesulfonic Acid Ethyl Dihydrogen Phosphate Butyrylthiocholine Phenserine DODECANESULFONATE ION 9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE (1R)-menthyl hexyl phosphonate group (1S)-menthyl hexyl phosphonate group ETHYL HYDROGEN DIETHYLAMIDOPHOSPHATE
Diseases		Congenital myasthenic syndrome
GWAS		Diverticular disease ( 30177863 28585551) Diverticulitis ( 28585551)	Alzheimer's disease biomarkers ( 23419831) Aspirin hydrolysis (plasma) ( 23508960) Blood protein levels ( 30072576 29875488) Butyrylcholinesterase levels ( 21862451) Cardiovascular disease risk factors ( 21943158) Fast beta electroencephalogram ( 28070124) FEV1 ( 30804560) Heart failure ( 20445134) Lung function (FEV1/FVC) ( 30804560) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Peak expiratory flow ( 30804560)
Interacting Genes		4 interacting genes: ACHE BCHE MRPS25 MUSK	1 interacting genes: COLQ
Entrez ID		8292	590
HPRD ID		04328	01519
Ensembl ID		ENSG00000206561	ENSG00000114200
Uniprot IDs		Q9Y215	P06276
PDB IDs		1VZJ	1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2PM8 2WID 2WIF 2WIG 2WIJ 2WIK 2WIL 2WSL 2XMB 2XMC 2XMD 2XMG 2XQF 2XQG 2XQI 2XQJ 2XQK 2Y1K 3DJY 3DKK 3O9M 4AQD 4AXB 4B0O 4B0P 4BBZ 4BDS 4TPK 4XII 5DYT 5DYW 5DYY 5K5E 5LKR 5NN0 6EMI 6EP4 6EQP 6EQQ 6ESJ 6ESY 6EUL 6EYF 6EZ2 6F7Q 6I0B 6I0C 6I2T 6QAA 6QAB 6QAC 6QAD 6QAE
Enriched GO Terms of Interacting Partners?
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