NAA10 and CDC25A

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (enzymatic study)
HPRD (two hybrid)

		NAA10	CDC25A
Description		N-alpha-acetyltransferase 10, NatA catalytic subunit	cell division cycle 25A
Image
GO Annotations	Cellular Component	Intracellular Nucleus Nucleolus Cytoplasm Cytosol Membrane NatA Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Peptide Alpha-N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Acetyltransferase Activity Ribosome Binding Peptide-serine-N-acetyltransferase Activity Peptide-glutamate-N-acetyltransferase Activity	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding Chaperone Binding
	Biological Process	DNA Packaging Protein Acetylation N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation N-terminal Peptidyl-serine Acetylation N-terminal Peptidyl-glutamic Acid Acetylation Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Cell Proliferation Response To Radiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Deubiquitination Cellular Response To UV Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Mitotic Cell Cycle Cell Division Regulation Of Cell Cycle Positive Regulation Of G2/MI Transition Of Meiotic Cell Cycle
Pathways			Transcription of E2F targets under negative control by DREAM complex Polo-like kinase mediated events Activation of ATR in response to replication stress Ub-specific processing proteases Cyclin E associated events during G1/S transition Cyclin A/B1/B2 associated events during G2/M transition Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Cyclin A:Cdk2-associated events at S phase entry Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 26502338)	Blood protein levels ( 28240269) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878) Household income (MTAG) ( 31844048) Loneliness (multivariate analysis) ( 27629369) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (beta blocking agents) ( 31015401) Medication use (diuretics) ( 31015401) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 27618447)
Interacting Genes		29 interacting genes: BCOR CALCOCO2 CDC25A CEP44 CREB3 EHMT2 FIP1L1 HIF1A HIF1AN HSPA4 KIFAP3 KRTAP10-3 KRTAP10-5 KRTAP10-7 MEOX2 NAA15 NAA16 NAA50 NAT1 NAT2 PDE4DIP PGK1 PSME2 RAB3IP RBCK1 RPL26 SSX2IP UBC ZBTB14	55 interacting genes: APP AR BTRC CAMK1D CCNA1 CCNB1 CCNE1 CCNI CDK1 CDK2 CDK5 CDKN3 CHEK1 CHEK2 CSNK1A1 CUL3 CUX1 DMD DUSP8 EEF1A1 EGFR FAM193B FBXW11 FGF21 FTH1 FZR1 HDAC11 HLA-C HRAS IL3RA LMO2 MAP3K5 MAPK14 MCM3AP MTAP NAA10 NFKBIB NFYA PEX19 PIM1 PKM POLR1D RAF1 ROCK1 SCYL1 SMAD3 SOX5 SRC UBB VAMP8 XPO1 YWHAB YWHAE YWHAQ YWHAZ
Entrez ID		8260	993
HPRD ID		02056	00305
Ensembl ID		ENSG00000102030	ENSG00000164045
Uniprot IDs		B7Z9N2 P41227	A0A024R2R6 D8KXX0 K7N7S0 P30304
PDB IDs		6C95 6C9M	1C25
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?