ZRSR2 and CLK2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZRSR2	CLK2
Description		zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2	CDC like kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex U2AF	Nucleus Nucleoplasm Nuclear Body Nuclear Speck
	Molecular Function	Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing	Protein Phosphorylation Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Response To Retinoic Acid Regulation Of RNA Splicing Negative Regulation Of Gluconeogenesis Protein Autophosphorylation
Pathways		mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS			Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		8 interacting genes: APP CLK2 SDCBP2 SRSF1 SRSF2 SSX2IP U2AF1 U2AF2	28 interacting genes: AKT1 CLK3 CPSF7 ECE1 GMCL1 KLHL2 LNX1 LUZP4 MRPL4 PRPF38A PTPN1 RBM39 RNPS1 RSRP1 SDCBP SRPK2 SRRM1 TRIM27 U2AF1 UBE2I UBL5 YTHDC1 YWHAG ZNF263 ZNF394 ZNF398 ZNF473 ZRSR2
Entrez ID		8233	1196
HPRD ID		02068	04289
Ensembl ID		ENSG00000169249	ENSG00000176444
Uniprot IDs		Q15696	A8K7I0 B7Z8N6 P49760
PDB IDs			3NR9 5UNP 6FYI 6FYK 6FYL 6KHE
Enriched GO Terms of Interacting Partners?
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