LZTR1 and MED7

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		LZTR1	MED7
Description		leucine zipper like transcription regulator 1	mediator complex subunit 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Endomembrane System Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Membrane	Ubiquitin Ligase Complex Nucleoplasm Transcription Factor Complex Mediator Complex Nuclear Body
	Molecular Function	DNA-binding Transcription Factor Activity Ras GTPase Binding	Transcription Coactivator Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Nucleic Acid-templated Transcription
Pathways			PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Medication use (thyroid preparations) ( 31015401)
Interacting Genes		54 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MRAS MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3	22 interacting genes: CTDP1 DNMT3L ESR1 ESR2 HAUS1 HGS HNF4A IKBKG LZTR1 MED31 MED8 MED9 PCBD2 PML RBFOX2 RELA RHOXF2 SREBF1 TRIM15 TRIM29 UBE2I ZSCAN1
Entrez ID		8216	9443
HPRD ID		08992	05439
Ensembl ID		ENSG00000099949	ENSG00000155868
Uniprot IDs		A0A384NL67 Q8N653	O43513 Q6IAZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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