VANGL1 and SMYD3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		VANGL1	SMYD3
Description		VANGL planar cell polarity protein 1	SET and MYND domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Lateral Plasma Membrane	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Complex Binding RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding
	Biological Process	Multicellular Organism Development Pigmentation Wnt Signaling Pathway, Planar Cell Polarity Pathway	Nucleosome Assembly Negative Regulation Of Protein Kinase Activity Myotube Cell Development Positive Regulation Of Peptidyl-serine Phosphorylation Histone Lysine Methylation Establishment Of Protein Localization Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Dexamethasone Stimulus
Pathways			PKMTs methylate histone lysines
Drugs
Diseases		Caudal regression syndrome and Sirenomelia Spina bifida
GWAS		Gut microbiota (bacterial taxa) ( 27694959) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Optic disc size ( 31809533)	Bipolar disorder ( 31043756) Blood metabolite levels ( 26401656) Coffee consumption ( 31046077) Fractional exhaled nitric oxide (childhood) ( 24315451) Obesity-related traits ( 23251661) Post bronchodilator FEV1 ( 26634245) Response to serotonin reuptake inhibitors in non-psychotic unipolar depression ( 26348319) Systemic lupus erythematosus ( 29848360) Upper eyelid sagging severity ( 24869959)
Interacting Genes		11 interacting genes: CD82 DVL1 DVL2 DVL3 GMFG LINC00839 NT5C3A RAPGEF5 SMYD3 SRPK1 THAP2	17 interacting genes: APP CAMK2B CYP39A1 EED EZH2 H3-4 H3-5 HELZ HSP90AA1 NDUFAB1 NFYB PBX2 POLR2K SCCPDH TRIT1 VANGL1 ZNF557
Entrez ID		81839	64754
HPRD ID		18279	12297
Ensembl ID		ENSG00000173218	ENSG00000185420
Uniprot IDs		A0A024R0E3 Q8TAA9	B3KN46 Q9H7B4
PDB IDs			3MEK 3OXF 3OXG 3OXL 3PDN 3QWP 3RU0 5CCL 5CCM 5EX0 5EX3 5HI7 5HQ8 5V37 5XXD 5XXG 5XXJ 5YJO 6IJL
Enriched GO Terms of Interacting Partners?
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