TXNDC5 and KRTAP4-2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TXNDC5	KRTAP4-2
Description		thioredoxin domain containing 5	keratin associated protein 4-2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Cytosol Keratin Filament
	Molecular Function	Protein Binding Isomerase Activity	Protein Binding
	Biological Process	Negative Regulation Of Apoptotic Process Apoptotic Cell Clearance Neutrophil Degranulation Cell Redox Homeostasis	Keratinization
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation	Keratinization
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) High chromosomal aberration frequency (chromatid type) ( 31586183)
Interacting Genes		26 interacting genes: APP AR BLZF1 EDEM3 EFEMP1 FLACC1 GMPPB KRT38 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 LHX4 MGAT5B NOTCH2NLA PJA1 PRDX2 RAB3IP SPRY2 TRIM23 TRIM42 TRIP6	75 interacting genes: ADAMTSL4 ALDH3B1 AMOTL2 AQP1 ATG9A AXIN1 BYSL CHIC2 CHRD CRCT1 CREB5 DLGAP2 DOCK2 FAM74A4 GLRX3 GNMT HOXA1 HPCAL1 HSD3B7 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LASP1 LCE1B LCE2A LCE3C LCE3E LCE4A LNX1 MEOX2 NECTIN3 NLK NOTCH2NLA NR1D2 NTAQ1 NUFIP2 OTX1 PDE9A PGLS PIN1 PLSCR1 POM121L8P PRKAB2 PRKAG1 PSMA6 RASSF5 RGS20 SDC3 SHFL SLC23A1 SLC25A10 SPATA24 SPATA3 SPRY1 TCEANC TINAGL1 TRIM42 TXNDC5 TYRO3 ZBTB24 ZNF124 ZNF20 ZNF417 ZNF559 ZNF581 ZNF688
Entrez ID		81567	85291
HPRD ID		18249	13944
Ensembl ID		ENSG00000239264	ENSG00000244537
Uniprot IDs		A0A024QZV0 Q8NBS9	Q9BYR5
PDB IDs		2DIZ 3UJ1 3UVT 3WGD 3WGE 3WGX
Enriched GO Terms of Interacting Partners?
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