TMX1 and SULT2A1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		TMX1	SULT2A1
Description		thioredoxin related transmembrane protein 1	sulfotransferase family 2A member 1
Image
GO Annotations	Cellular Component	Cell Endoplasmic Reticulum Membrane Integral Component Of Membrane	Cytosol
	Molecular Function	Disulfide Oxidoreductase Activity	Protein Binding Sulfotransferase Activity Bile-salt Sulfotransferase Activity Steroid Sulfotransferase Activity
	Biological Process	Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Oxidation-reduction Process	Ethanol Catabolic Process Steroid Metabolic Process Lipid Catabolic Process Regulation Of Lipid Metabolic Process Bile Acid Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways			Cytosolic sulfonation of small molecules PPARA activates gene expression
Drugs			Prasterone Adenosine-3'-5'-Diphosphate Aetiocholanolone Mercuric iodide
Diseases
GWAS		Cancer ( 29299148) Nonsyndromic cleft lip with or without cleft palate ( 28087736) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)	Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 30072576) Cleft palate ( 30452639) Dehydroepiandrosterone sulphate levels ( 21533175) Gallstone disease ( 30504769 27094239) Serum metabolite levels ( 23093944) Sex hormone levels ( 26014426) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		3 interacting genes: FAS SPI1 SULT2A1	6 interacting genes: GDF15 PRDX4 STAT3 STK3 SULT1B1 TMX1
Entrez ID		81542	6822
HPRD ID		15590	00502
Ensembl ID		ENSG00000139921	ENSG00000105398
Uniprot IDs		Q9H3N1	A8K015 Q06520
PDB IDs		1X5E	1EFH 1J99 1OV4 2QP3 2QP4 3F3Y 4IFB
Enriched GO Terms of Interacting Partners?
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