THAP7 and PPP3CC

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		THAP7	PPP3CC
Description		THAP domain containing 7	protein phosphatase 3 catalytic subunit gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Nuclear Speck Nuclear Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Mitochondrion Cytosol Calcineurin Complex Glutamatergic Synapse Presynaptic Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Metal Ion Binding Protein N-terminus Binding C2H2 Zinc Finger Domain Binding	Protein Binding Calmodulin Binding Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated	Protein Dephosphorylation Brain Development Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Positive Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways			Activation of BAD and translocation to mitochondria DARPP-32 events
Drugs
Diseases
GWAS			General risk tolerance (MTAG) ( 30643258) HIV-1 viral setpoint ( 20205591) Verbal declarative memory ( 25648963)
Interacting Genes		35 interacting genes: APP CCDC85B CCNDBP1 EHMT2 FBXO7 GNAI1 GOLGA2 H3C1 H4C1 HCFC1 HDAC3 KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 LNX1 LURAP1 LZTS2 MAP1LC3B MDFI MID2 MTUS2 NOTCH2NLA PELI2 PHC2 PIN1 PPP3CC SET TAF1B TFIP11 THAP11 TRAF1 TRAF2 ZDHHC17	11 interacting genes: AMPH APP BCL2 BMPR1B CABIN1 CSNK2B HAX1 ITPKC SDC2 TGFBR1 THAP7
Entrez ID		80764	5533
HPRD ID		15500	00236
Ensembl ID		ENSG00000184436	ENSG00000120910
Uniprot IDs		Q9BT49	P48454
PDB IDs
Enriched GO Terms of Interacting Partners?
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