UBXN6 and DERL1

Number of citations of the paper that reports this interaction (PubMedID 19275885)
11

Data Source:
BioGRID (pull down)

		UBXN6	DERL1
Description		UBX domain protein 6	derlin 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosomal Membrane Endosome Microtubule Organizing Center Cytosol Extrinsic Component Of Membrane Early Endosome Membrane Late Endosome Membrane Protein-containing Complex Extracellular Exosome	Hrd1p Ubiquitin Ligase ERAD-L Complex Early Endosome Late Endosome Endoplasmic Reticulum Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Derlin-1-VIMP Complex Derlin-1 Retrotranslocation Complex Signal Recognition Particle
	Molecular Function	Protein Binding	Protease Binding Protein Binding Ubiquitin Protein Ligase Binding Signaling Receptor Activity MHC Class I Protein Binding Identical Protein Binding ATPase Binding Misfolded Protein Binding Ubiquitin-specific Protease Binding
	Biological Process	Macroautophagy Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway ERAD Pathway	Protein Folding Response To Unfolded Protein Viral Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Positive Regulation Of Protein Ubiquitination Protein Destabilization Positive Regulation Of Protein Binding ERAD Pathway Establishment Of Protein Localization Transmembrane Transport ER-associated Misfolded Protein Catabolic Process
Pathways			ABC-family proteins mediated transport N-glycan trimming in the ER and Calnexin/Calreticulin cycle Defective CFTR causes cystic fibrosis E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Delta-5 desaturase activity response to n3-polyunsaturated fat supplement ( 29246731) Multiple sclerosis ( 31604244)	Metabolite levels ( 23823483)
Interacting Genes		11 interacting genes: APP DERL1 GSK3B MAGEA4 MCL1 NLGN3 SMURF1 TRIM39 UBC UFD1 VCP	11 interacting genes: AMFR APP CFTR HLA-A LMNA MELTF RHO SELENOS TCF25 UBXN6 VCP
Entrez ID		80700	79139
HPRD ID		18253	12302
Ensembl ID		ENSG00000167671	ENSG00000136986
Uniprot IDs		Q9BZV1	A0A024R9G3 E5RGY0 Q9BUN8
PDB IDs			5GLF
Enriched GO Terms of Interacting Partners?
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