ADAM12 and TUBGCP2

		ADAM12	TUBGCP2
Description		ADAM metallopeptidase domain 12	tubulin gamma complex associated protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Plasma Membrane Integral Component Of Membrane	Spindle Pole Equatorial Microtubule Organizing Center Gamma-tubulin Complex Nucleoplasm Centrosome Microtubule Organizing Center Cytosol Cytoplasmic Microtubule Gamma-tubulin Small Complex Membrane
	Molecular Function	Metalloendopeptidase Activity Protein Binding Metallopeptidase Activity SH3 Domain Binding Metal Ion Binding	Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Proteolysis Cell Adhesion Myoblast Fusion Extracellular Matrix Organization Positive Regulation Of Angiogenesis	Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Microtubule Nucleation By Interphase Microtubule Organizing Center Protein-containing Complex Assembly
Pathways		Signaling by EGFR Invadopodia formation	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Endometrial cancer ( 24096698) Extremely high intelligence ( 29731509) Heel bone mineral density ( 30598549) Intraocular pressure ( 30054594) Itch intensity from mosquito bite ( 28199695) Loneliness ( 27629369) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Mild influenza (H1N1) infection ( 26379185) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070 27021288) Placental abruption ( 29884306) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Visceral fat ( 22589738)	Mild influenza (H1N1) infection ( 26379185) Nonunion in individuals with fractures ( 30680360)
Interacting Genes		12 interacting genes: ACTN2 EGF FSTL3 GRB2 IGFBP3 IGFBP5 PACSIN3 PIK3R1 SH3D19 SRC TUBGCP2 YES1	11 interacting genes: ADAM12 BNIP3 C1R CALY CTSE H3C1 INPP5A KIF14 PCNT POLR2E UBC
Entrez ID		8038	10844
HPRD ID		04092	18245
Ensembl ID		ENSG00000148848	ENSG00000130640
Uniprot IDs		A8K6G4 O43184 U5NE98	Q53EQ3 Q9BSJ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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