EPC1 and RINT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EPC1	RINT1
Description		enhancer of polycomb homolog 1	RAD50 interactor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Dsl1/NZR Complex
	Molecular Function	Histone Acetyltransferase Activity Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Vascular Smooth Muscle Cell Differentiation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition	Retrograde Vesicle-mediated Transport, Golgi To ER Cell Cycle Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
Pathways		HATs acetylate histones Transcriptional Regulation by E2F6	COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483) Platelet distribution width ( 27863252) Sexual dysfunction (female) ( 22509378)
Interacting Genes		6 interacting genes: E2F6 HOPX KRT15 MBTD1 RINT1 TRIM27	55 interacting genes: ARNT2 BNIP3L C1orf109 CCDC121 CCDC146 CEP57L1 CSPP1 CWF19L2 DCX EPC1 FAM107A FAM110A FAM124B FAM161A FAM81B FAM90A1 FANCG GFI1B GRAP2 HDAC4 HGS LMO2 LSP1P3 MCM7 PCM1 PIK3R2 PIMREG PRPF31 PSTPIP1 RAD50 RB1 RBL1 RBL2 RBM41 RIBC1 RNF6 RSRC2 RTP5 SCNM1 SFR1 SGF29 SH2D4A SMARCB1 SMARCE1 SNW1 SPTBN1 STRN TEX9 TXLNA VPS37C XPNPEP1 ZNF655 ZNF688 ZNF697 ZW10
Entrez ID		80314	60561
HPRD ID		09941	15250
Ensembl ID		ENSG00000120616	ENSG00000135249
Uniprot IDs		Q9H2F5	Q6NUQ1
PDB IDs		6NFX
Enriched GO Terms of Interacting Partners?
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