RUFY1 and TXNDC17

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		RUFY1	TXNDC17
Description		RUN and FYVE domain containing 1	thioredoxin domain containing 17
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GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding	Peroxidase Activity Protein Binding Protein-disulfide Reductase Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis	Tumor Necrosis Factor-mediated Signaling Pathway Oxidation-reduction Process Cellular Oxidant Detoxification
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730)	LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		16 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TXNDC17 UTP25	9 interacting genes: AVP DYNLL1 EXOSC8 INS OXT PIGS RUFY1 TINF2 TXNRD1
Entrez ID		80230	84817
HPRD ID		15282	11656
Ensembl ID		ENSG00000176783	ENSG00000129235
Uniprot IDs		A8K7B1 Q96T51	A0A140VJY7 Q9BRA2
PDB IDs		2YQM 2YW8	1WOU
Enriched GO Terms of Interacting Partners?
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