RIN3 and POLR3F

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		RIN3	POLR3F
Description		Ras and Rab interactor 3	RNA polymerase III subunit F
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GO Annotations	Cellular Component	Early Endosome Cytosol Cytoplasmic Vesicle	Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding	Double-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	Endocytosis Signal Transduction Positive Regulation Of GTPase Activity	Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways		RAB GEFs exchange GTP for GDP on RABs	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Alzheimer's disease ( 31473137) Alzheimer's disease (late onset) ( 30617256 24162737) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Breast cancer ( 25751625 29059683) Chronic obstructive pulmonary disease ( 28166215 30804561 25101718) Chronic obstructive pulmonary disease (moderate to severe) ( 24621683) Chronic obstructive pulmonary disease (severe) ( 24621683) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Composite immunoglobulin trait (IgA/IgM) ( 28628107) Dialysis-related mortality ( 21546767) Eosinophil counts ( 27863252) Estimated glomerular filtration rate ( 31152163) FEV1 ( 30804560) Granulocyte count ( 27863252) Local histogram emphysema pattern ( 25006744) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 26635082 30804560) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Paget's disease ( 21623375) Plateletcrit ( 27863252) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Pulse pressure ( 30224653) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systemic juvenile idiopathic arthritis ( 27927641) White blood cell count ( 27863252)
Interacting Genes		41 interacting genes: ASB3 ASB8 BIN1 CRK CRKL CSRP3 CYP2C8 CYP46A1 DOK3 EPS8L2 EZH2 GATA1 GRAP2 ID2 KCTD17 LCK MPEG1 MT2A PLB1 POLR3F PSMD9 RAB5A RAB5B RAB5C RABAC1 RGS2 RTL8B SPATA12 SPRY4 SUV39H1 SYMPK TENT5A TGM1 TM4SF19 TNFAIP1 TSC1 TSSK3 ZBTB24 ZNF639 ZNF655 ZNF71	15 interacting genes: BDP1 BRF1 ERG28 GTF3C4 KAT5 LRIF1 NINL PRPF4B RIN3 STC2 SUV39H2 TBP TNS2 UBE2G2 WDR89
Entrez ID		79890	10621
HPRD ID		11494	15156
Ensembl ID		ENSG00000100599	ENSG00000132664
Uniprot IDs		Q6NSK7 Q6ZRC2 Q86U22 Q8TB24	Q05DB8 Q9H1D9
PDB IDs		3U23 4WCI	2DK5 2YU3
Enriched GO Terms of Interacting Partners?
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