ALG13 and PITX1

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		ALG13	PITX1
Description		ALG13 UDP-N-acetylglucosaminyltransferase subunit	paired like homeodomain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane	Nuclear Chromatin Nucleus Transcription Factor Complex Cytoplasm
	Molecular Function	RNA Binding N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Activity Thiol-dependent Ubiquitinyl Hydrolase Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Dolichol-linked Oligosaccharide Biosynthetic Process Proteolysis	Skeletal System Development Anatomical Structure Morphogenesis Branchiomeric Skeletal Muscle Development Pituitary Gland Development Embryonic Hindlimb Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Myoblast Fate Commitment Cartilage Development
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
Drugs
Diseases			Congenital clubfoot; Congenital talipes equinovarus
GWAS		Rosacea symptom severity ( 29771307)	Atrial fibrillation ( 29237688) Bulimia nervosa ( 23568457) Colorectal cancer ( 30529582 24836286 23263487) Colorectal cancer or advanced adenoma ( 30510241) Height ( 20881960 25429064 23563607 31562340 18391951) Immune response to anthrax vaccine ( 22658931) Testicular germ cell tumor ( 28604732 23666240)
Interacting Genes		9 interacting genes: ATN1 ATXN1L HOXA1 MAPKBP1 PITX1 RBFOX1 RERE RHOU TRIM14	27 interacting genes: ALG13 C1orf94 CDX4 DVL3 EGR1 FOXO1 GOLGA2 HGS IPO13 LZTS2 MAGED1 MGAT5B NEUROD1 NR5A1 PLSCR1 POU1F1 PRR20A RBPMS RFX6 RHOXF2 RNF31 SMARCA2 SPAG8 TRAPPC2 TRIM23 UPF2 ZBTB32
Entrez ID		79868	5307
HPRD ID		06542	03688
Ensembl ID		ENSG00000101901	ENSG00000069011
Uniprot IDs		A0A087WT15 A0A087WX43 Q9NP73	P78337 X5D9A5
PDB IDs
Enriched GO Terms of Interacting Partners?
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