GSTCD and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		GSTCD	SUV39H2
Description		glutathione S-transferase C-terminal domain containing	suppressor of variegation 3-9 homolog 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Extracellular Exosome	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	Molecular_function Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Biological_process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 28166215) Copper levels ( 26025379) FEV1 ( 30804560) Lung function (FEV1) ( 28166213 24023788) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 28166213 30804560) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Peak expiratory flow ( 30804560) Post bronchodilator FEV1 ( 26634245) Pulmonary function ( 20010834 20010835) Pulmonary function (smoking interaction) ( 23284291)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		7 interacting genes: CLNK DAPP1 KDM1A PRMT6 STAT3 SUV39H2 TNS4	40 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CCDC151 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		79807	79723
HPRD ID		07823	07580
Ensembl ID		ENSG00000138780	ENSG00000152455
Uniprot IDs		B7Z8J7 Q8NEC7	Q9H5I1
PDB IDs			2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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