KCTD17 and TCHP

Number of citations of the paper that reports this interaction (PubMedID 25270598)
43

Data Source:
BioGRID (pull down, enzymatic study)

		KCTD17	TCHP
Description		potassium channel tetramerization domain containing 17	trichoplein keratin filament binding
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cul3-RING Ubiquitin Ligase Complex	Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Desmosome Keratin Filament Apical Cortex Ciliary Transition Fiber
	Molecular Function	Protein Binding Identical Protein Binding Cullin Family Protein Binding	Protein Binding
	Biological Process	Cell Projection Organization Endoplasmic Reticulum Calcium Ion Homeostasis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cilium Assembly Protein Homooligomerization	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Iron status biomarkers (ferritin levels) ( 28334935) Mean corpuscular hemoglobin concentration ( 28453575) Red blood cell traits ( 23222517)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		19 interacting genes: AQP1 CRK CUL3 DMC1 LNX1 LRRC18 NIF3L1 NUDT18 PLCG2 PSMA1 RBX1 RIN3 RWDD4 STK16 SUV39H2 TCHP TINF2 TUBGCP4 UBE2D1	23 interacting genes: CCDC172 CCDC85B CDR2 DYDC1 IFFO1 KCTD17 KRT14 KRT15 KRT16 KRT18 KRT40 KRT5 KRT6A KRT8 LZTS2 MIPOL1 MKRN3 NAB2 NDOR1 NME7 TEX11 TRIM27 VIM
Entrez ID		79734	84260
HPRD ID		07764	14403
Ensembl ID		ENSG00000100379	ENSG00000139437
Uniprot IDs		A0A087WX35 Q8N5Z5	A0A024RBM9 Q9BT92
PDB IDs		5A6R
Enriched GO Terms of Interacting Partners?
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