HMBOX1 and REEP6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HMBOX1	REEP6
Description		homeobox containing 1	receptor accessory protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body	Photoreceptor Inner Segment Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Clathrin-coated Vesicle Membrane Rod Spherule Apical Part Of Cell
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity	Regulation Of Intracellular Transport Detection Of Light Stimulus Involved In Visual Perception
Pathways			Olfactory Signaling Pathway
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688	20 interacting genes: ADAT3 COQ8A FAM160A2 HMBOX1 IZUMO4 LITAF LMNA NDRG4 PTPN9 RPS20 SCAMP4 SDCBP SNX1 SNX15 SPG21 TMEM259 TNS2 TXN2 ZFYVE21 ZNF554
Entrez ID		79618	92840
HPRD ID		07964	16629
Ensembl ID		ENSG00000147421	ENSG00000115255
Uniprot IDs		D3DSU2 Q6NT76	A0A1L5BXV2 Q96HR9
PDB IDs		2CUF 4J19
Enriched GO Terms of Interacting Partners?
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