ABHD16A and UPF1

Number of citations of the paper that reports this interaction (PubMedID 15231747)
56

Data Source:
HPRD (two hybrid)

		ABHD16A	UPF1
Description		abhydrolase domain containing 16A, phospholipase	UPF1 RNA helicase and ATPase
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nuclear Chromosome, Telomeric Region Chromatin P-body Nucleus Nucleoplasm Cytoplasm Cytosol Exon-exon Junction Complex Supraspliceosomal Complex
	Molecular Function	Phospholipase Activity Lysophospholipase Activity Protein Binding Acylglycerol Lipase Activity	Chromatin Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Telomeric DNA Binding
	Biological Process	Phosphatidylserine Catabolic Process Monoacylglycerol Catabolic Process Prostaglandin Catabolic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process, Endonucleolytic Cleavage-dependent Decay Nuclear-transcribed MRNA Catabolic Process DNA Replication DNA Repair MRNA Export From Nucleus Regulation Of Translational Termination Dosage Compensation By Inactivation Of X Chromosome Viral Process Telomere Maintenance Via Semi-conservative Replication Regulation Of Telomere Maintenance Cell Cycle Phase Transition Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization Histone MRNA Catabolic Process Cellular Response To Lipopolysaccharide Cellular Response To Interleukin-1
Pathways			Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		20 interacting genes: ATP5MC3 CREB3 DNAJC1 DTX2 GPRC5C HM13 HNRNPA1 IFITM1 MLH1 MT-ND3 MT-ND4 PILRB PTGS2 RETREG3 RNF5 SAFB SPAG7 TMEM147 TMEM222 UPF1	36 interacting genes: ABHD16A ACRV1 ACSS2 AP1G1 ATR CNN1 CSNK2B DCP1A DCP2 DHPS DXO EIF3A EIF3B EIF4A3 EXOSC2 EXOSC4 GNPTG HIRA LDB1 LSM8 NADSYN1 NDRG1 NDUFB10 NOTCH3 PLEKHA5 PLEKHB2 POLR2A RHOXF2 RPRD2 SMG1 SMG5 STAU1 UPF2 UPF3A UPF3B XRN1
Entrez ID		7920	5976
HPRD ID		15929	03254
Ensembl ID		ENSG00000204427	ENSG00000005007
Uniprot IDs		A0A1U9X777 B3KNX9 O95870	A0A024R7L5 A0A024R7L8 B3KY55 Q92900
PDB IDs			2GJK 2GK6 2GK7 2IYK 2WJV 2WJY 2XZO 2XZP 6EJ5
Enriched GO Terms of Interacting Partners?
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