BRCC3 and SNAPC5

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		BRCC3	SNAPC5
Description		BRCA1/BRCA2-containing complex subunit 3	small nuclear RNA activating complex polypeptide 5
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nuclear Ubiquitin Ligase Complex Spindle Pole Nucleus Nucleoplasm Cytoplasm Cytosol BRCA1-A Complex BRISC Complex	Nucleus Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Enzyme Regulator Activity Polyubiquitin Modification-dependent Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Metal Ion Binding Lys63-specific Deubiquitinase Activity	RNA Polymerase III General Transcription Initiation Factor Activity DNA-binding Transcription Factor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	DNA Repair Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Cell Cycle Response To X-ray Response To Ionizing Radiation Protein Deubiquitination Positive Regulation Of DNA Repair Regulation Of Catalytic Activity Cell Division Protein K63-linked Deubiquitination Histone H2A K63-linked Deubiquitination Signal Transduction Involved In G2 DNA Damage Checkpoint	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III
Pathways		Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs		Zinc
Diseases
GWAS		Venous thromboembolism ( 31676865)
Interacting Genes		9 interacting genes: BRCA1 FANCG IFNAR1 NUMA1 SNAPC5 SUMO2 UBC UBE2D1 UIMC1	14 interacting genes: AMOT BATF BRCC3 CYTH4 DDIT3 JUN NDEL1 NMI NOL4 NUDT10 NUP62 SNAPC1 SNAPC4 ZNRD2
Entrez ID		79184	10302
HPRD ID		06465	16183
Ensembl ID		ENSG00000185515	ENSG00000174446
Uniprot IDs		P46736	A0A024R5X1 O75971
PDB IDs		6H3C 6R8F
Enriched GO Terms of Interacting Partners?
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