LENG1 and TFIP11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LENG1	TFIP11
Description		leukocyte receptor cluster member 1	tuftelin interacting protein 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nuclear Chromosome, Telomeric Region Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Nuclear Speck Extracellular Matrix U2-type Post-mRNA Release Spliceosomal Complex Catalytic Step 2 Spliceosome
	Molecular Function	Molecular_function Protein Binding	Nucleic Acid Binding Protein Binding
	Biological Process	Biological_process	Spliceosomal Complex Disassembly MRNA Splicing, Via Spliceosome RNA Processing Biomineral Tissue Development Negative Regulation Of Protein Complex Assembly Protection From Non-homologous End Joining At Telomere Negative Regulation Of Protein Binding Negative Regulation Of DNA Ligase Activity Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		36 interacting genes: APP BANP CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CDR2 CEP57L1 CEP70 FSD2 GOLGA2 KASH5 KIFC3 KLF10 KRT31 KRT40 LDOC1 MID2 MTUS2 NAB2 NAGK NECAB2 OSGEP PAK5 PDE4DIP PNMA1 ROPN1 STX11 TCF4 TFIP11 TMEM239 TRIM27 TRIM54 USHBP1	128 interacting genes: ABI2 AIMP2 ANKRD11 ARHGEF9 ARMC7 ARMCX1 ARNT2 ATP5PO AXIN1 BCL6 BMF C1orf109 C2CD6 CARD9 CCDC116 CCDC121 CCDC146 CCDC151 CCDC196 CCDC42 CCDC68 CCHCR1 CCND3 CCNG1 CCNL1 CCP110 CENPU CEP57 CEP57L1 CFAP206 COQ8A COX5B DGCR6 DISC1 EAF2 EIF3A FAM13C FAM156A FAM161A FAM50B FANCG GCC1 GEM GNG4 GOLGA1 GOLGA2 GPS2 GRAP2 HAUS1 HMG20B HOOK1 IKBIP IL16 IMP3 KANSL1 KRT20 KRT6A KRT6B KRT6C KRT8 LATS1 LCA5L LENG1 LIN37 LMO1 LMO4 LSM3 LSP1P3 MCM7 MDM2 METTL17 MTFR2 NDC80 NDE1 NDN NFU1 OIP5 PBX4 PCM1 PDE4DIP POLL POLR1C PPP1R16A PPP1R16B PPP1R18 PRPF31 PSTPIP1 RCOR3 RHNO1 RNF6 RRP7A RXRB S100P SAP30BP SCNM1 SFR1 SH2D4A SH3GLB1 SMARCB1 SMARCE1 SNRPB SNW1 SNX20 SSX2IP STRN SYCE1 TCAF1 TDP2 TFPT THAP7 THAP8 TNNT1 TP53 TRAF3IP3 TRAPPC4 TSHZ3 TSPYL4 TUFT1 TXLNA USP6 USP7 VPS37C ZC2HC1C ZFYVE26 ZGPAT ZMAT2 ZNF417 ZSCAN12
Entrez ID		79165	24144
HPRD ID		13985	11628
Ensembl ID		ENSG00000105617	ENSG00000100109
Uniprot IDs		Q96BZ8	A0A024R1I7 Q9UBB9
PDB IDs
Enriched GO Terms of Interacting Partners?
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