BRPF1 and PBXIP1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		BRPF1	PBXIP1
Description		bromodomain and PHD finger containing 1	PBX homeobox interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane MOZ/MORF Histone Acetyltransferase Complex	Nucleus Cytosol Microtubule Membrane
	Molecular Function	DNA Binding Protein Binding Histone Acetyltransferase Activity (H3-K23 Specific) Metal Ion Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Histone H3 Acetylation Histone H3-K23 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction By P53 Class Mediator	Multicellular Organism Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)
Interacting Genes		3 interacting genes: GTF2H1 H3C14 PBXIP1	22 interacting genes: BRPF1 CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GMCL1 GRB2 MDFI MDM2 MORF4L1 PCBD2 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3
Entrez ID		7862	57326
HPRD ID		03875	17823
Ensembl ID		ENSG00000156983	ENSG00000163346
Uniprot IDs		P55201	B4E0K4 Q96AQ6
PDB IDs		2D9E 2RS9 2X35 2X4W 2X4X 2X4Y 3L42 3MO8 4LC2 4QYD 4QYL 4UYE 5C6S 5C7N 5C85 5C87 5C89 5D7X 5DY7 5DYA 5DYC 5E3D 5E3G 5EM3 5EPR 5EPS 5EQ1 5ERC 5ETB 5ETD 5EV9 5EVA 5EWC 5EWD 5EWH 5EWV 5EWW 5FFV 5FFW 5FFY 5FG4 5FG5 5G4R 5G4S 5MWG 5MWH 5MWZ 5MYG 5O4S 5O4T 5O55 5O5A 5O5F 5O5H 5OV8 5OWA 5OWB 5OWE 5T4U 5T4V 6EKQ 6U04
Enriched GO Terms of Interacting Partners?
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