SLC30A1 and CENPF

		SLC30A1	CENPF
Description		solute carrier family 30 member 1	centromere protein F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Endoplasmic Reticulum Golgi Apparatus Plasma Membrane T-tubule Nuclear Membrane Schaffer Collateral - CA1 Synapse Integral Component Of Postsynaptic Density Membrane	Chromosome, Centromeric Region Kinetochore Chromatin Spindle Pole Condensed Chromosome Outer Kinetochore Cell Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Centrosome Spindle Cytosol Axoneme Nuclear Matrix Midbody Ciliary Basal Body Pronucleus Perinuclear Region Of Cytoplasm Ciliary Transition Fiber
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding Calcium Channel Inhibitor Activity	Chromatin Binding Protein Binding Protein C-terminus Binding Transcription Factor Binding Protein Homodimerization Activity Dynein Complex Binding
	Biological Process	In Utero Embryonic Development Zinc Ion Transport Cellular Calcium Ion Homeostasis Cellular Zinc Ion Homeostasis Negative Regulation Of Neurotransmitter Secretion Calcium Ion Import Cadmium Ion Transmembrane Transport Zinc Ion Transmembrane Transport Negative Regulation Of Zinc Ion Transmembrane Import Detoxification Of Cadmium Ion Negative Regulation Of Calcium Ion Import	Mitotic Cell Cycle Kidney Development Chromosome Segregation Mitotic Spindle Assembly Checkpoint Muscle Organ Development Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Regulation Of Striated Muscle Tissue Development Ventricular System Development Cell Differentiation Response To Drug Negative Regulation Of Transcription, DNA-templated Cell Division Metaphase Plate Congression Kinetochore Assembly Regulation Of Cell Cycle DNA Biosynthetic Process
Pathways		Zinc efflux and compartmentalization by the SLC30 family	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Polo-like kinase mediated events Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Hypertension ( 21347282)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Lung function (FVC) ( 30061609) Response to antineoplastic agents ( 21659360)
Interacting Genes		3 interacting genes: CENPF MTNR1A MTNR1B	16 interacting genes: BRAP CENPE CHMP2B FNTA FNTB HSD11B1 IRF6 KLHL41 NDEL1 NUP133 PLOD2 SLC30A1 SLC4A1AP SNAP25 SVIL TOP3B
Entrez ID		7779	1063
HPRD ID		15366	02582
Ensembl ID		ENSG00000170385	ENSG00000117724
Uniprot IDs		Q9Y6M5	P49454
PDB IDs
Enriched GO Terms of Interacting Partners?
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