ZNF165 and PDLIM7

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZNF165	PDLIM7
Description		zinc finger protein 165	PDZ and LIM domain 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Stress Fiber Ruffle Nucleoplasm Cytosol Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Filamentous Actin
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding
	Biological Process	Myelination Negative Regulation Of Transcription, DNA-templated	Ossification Receptor-mediated Endocytosis Axon Guidance Heart Development Actin Cytoskeleton Organization Positive Regulation Of Osteoblast Differentiation Muscle Structure Development
Pathways			RET signaling
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Estimated glomerular filtration rate ( 31451708) Hepcidin/ferritin ratio ( 27846281) Moderate to vigorous physical activity levels ( 29899525) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730)	Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		22 interacting genes: AHCYL1 CCDC130 CCDC85B DVL2 ELOA2 EMD EWSR1 FAM124A GPATCH2L KAT7 KRT40 KRTAP10-3 KRTAP10-7 KRTAP4-12 MID2 PDLIM7 SCAND1 SUV39H1 ZKSCAN8 ZNF24 ZNF250 ZNF446	34 interacting genes: AP5B1 BSG CCDC185 DGCR6 ENKD1 FNDC11 GEM GFAP HNRNPD IQGAP1 MDM2 PAK5 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		7718	9260
HPRD ID		02903	10436
Ensembl ID		ENSG00000197279	ENSG00000196923
Uniprot IDs		P49910 Q53Z40	Q9NR12
PDB IDs			2Q3G
Enriched GO Terms of Interacting Partners?
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