WIPF1 and FASTK

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		WIPF1	FASTK
Description		WAS/WASL interacting protein family member 1	Fas activated serine/threonine kinase
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytosol Actin Filament Actin Cytoskeleton Actin Cortical Patch Cytoplasmic Vesicle	Mitochondrial Matrix
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Actin Filament Binding	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Fas-activated Serine/threonine Kinase Activity
	Biological Process	Actin Cortical Patch Assembly Endocytosis Actin Polymerization Or Depolymerization Regulation Of Cell Shape Actin Filament-based Movement Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Actin Nucleation Actin Cortical Patch Localization Response To Other Organism Protein-containing Complex Assembly	Protein Phosphorylation Regulation Of RNA Splicing Apoptotic Signaling Pathway
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Pulse pressure ( 27841878) Resting heart rate ( 27798624) Systolic blood pressure ( 27841878) Urate levels (BMI interaction) ( 25811787)	Eyebrow thickness ( 26926045)
Interacting Genes		22 interacting genes: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CDC42 CRKL CTTN FASTK GRB2 HCK HOMER3 ITSN2 NCK1 PRKCQ PRPF40A SEC24C WAS WASL WBP4 WWP2 ZAP70	6 interacting genes: CALCOCO2 MDFI PRPF31 RBPMS TIA1 WIPF1
Entrez ID		7456	10922
HPRD ID		03835	07368
Ensembl ID		ENSG00000115935	ENSG00000164896
Uniprot IDs		A0A140VJZ9 O43516 Q2YDC4	A0A090N8I0 A0A090N8Z7 Q14296
PDB IDs		2A41
Enriched GO Terms of Interacting Partners?
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