VIP and VIPR2

Number of citations of the paper that reports this interaction (PubMedID 10801840)
33

Data Source:
HPRD (in vitro, in vivo)

		VIP	VIPR2
Description		vasoactive intestinal peptide	vasoactive intestinal peptide receptor 2
Image
GO Annotations	Cellular Component	Extracellular Region Neuron Projection Perikaryon	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Protein Binding Peptide Hormone Receptor Binding	G Protein-coupled Receptor Activity Vasoactive Intestinal Polypeptide Receptor Activity G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Body Fluid Secretion Learning Or Memory Positive Regulation Of Cell Proliferation Positive Regulation Of Epinephrine Secretion Regulation Of Protein Localization Negative Regulation Of Apoptotic Process Negative Regulation Of Potassium Ion Transport Positive Regulation Of Protein Catabolic Process Epinephrine Secretion MRNA Stabilization Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Sensory Perception Of Pain Positive Regulation Of Penile Erection Prolactin Secretion Positive Regulation Of Blood Vessel Diameter	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Cell-cell Signaling Negative Regulation Of Smooth Muscle Cell Proliferation
Pathways		G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production	G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Body mass index ( 26426971) Chronotype ( 30696823) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600)	Corneal astigmatism ( 30306274) Myopia (pathological) ( 23406873) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Sub-foveal choroidal thickness ( 29844195)
Interacting Genes		8 interacting genes: MEOX2 MEP1A MME PRICKLE1 SGTA UBQLN4 VIPR1 VIPR2	4 interacting genes: ADCYAP1 APP ERBIN VIP
Entrez ID		7432	7434
HPRD ID		15950	03576
Ensembl ID		ENSG00000146469	ENSG00000106018
Uniprot IDs		P01282	P41587 X5D7Q6 X5DP12
PDB IDs		2RRH 2RRI	2X57
Enriched GO Terms of Interacting Partners?
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