UQCRC2 and UQCRC1

Number of citations of the paper that reports this interaction (PubMedID 11073949)
16

Data Source:
HPRD (in vitro)

		UQCRC2	UQCRC1
Description		ubiquinol-cytochrome c reductase core protein 2	ubiquinol-cytochrome c reductase core protein 1
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex IV Mitochondrial Processing Peptidase Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Mitochondrial Respiratory Chain Complex III Cytosol
	Molecular Function	Endopeptidase Activity Metalloendopeptidase Activity Protein Binding Protein-containing Complex Binding Metal Ion Binding	Ubiquinol-cytochrome-c Reductase Activity Ubiquitin Protein Ligase Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Protein Processing Involved In Protein Targeting To Mitochondrion Aerobic Respiration Response To Drug	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration Response To Activity Response To Alkaloid Oxidation-reduction Process
Pathways		Respiratory electron transport	Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE FAMOXADONE METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE UBIQUINONE-2	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Myxothiazol 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE FAMOXADONE METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE UBIQUINONE-2
Diseases
GWAS			Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Metabolite levels ( 23823483) Ulcerative colitis ( 28067908)
Interacting Genes		3 interacting genes: CACNA1A RTN4 UQCRC1	8 interacting genes: CYCS GPX1 HNRNPD KRAS NLGN3 RTN4 TRIM63 UQCRC2
Entrez ID		7385	7384
HPRD ID		01876	01875
Ensembl ID		ENSG00000140740	ENSG00000010256
Uniprot IDs		P22695	P31930
PDB IDs		5XTE 5XTH 5XTI	5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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