UGT2B15 and RAB8A

		UGT2B15	RAB8A
Description		UDP glucuronosyltransferase family 2 member B15	RAB8A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Endosome Centrosome Centriole Cytosol Plasma Membrane Cilium Synaptic Vesicle Endomembrane System Postsynaptic Density Trans-Golgi Network Transport Vesicle Midbody Phagocytic Vesicle Membrane Trans-Golgi Network Membrane Ciliary Basal Body Neuronal Cell Body Dendritic Spine Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Ciliary Base Non-motile Cilium Glutamatergic Synapse
	Molecular Function	Retinoic Acid Binding UDP-glycosyltransferase Activity Glucuronosyltransferase Activity	GTPase Activity Protein Binding GTP Binding Rab GTPase Binding GDP Binding Protein Kinase Binding Myosin V Binding
	Biological Process	Xenobiotic Metabolic Process Steroid Metabolic Process Cellular Glucuronidation	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Axonogenesis Protein Secretion Regulation Of Autophagy Regulation Of Exocytosis Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Post-translational Protein Modification Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Vesicle Fusion To Target Membrane Regulation Of Protein Transport Cilium Assembly Protein Localization To Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Vesicle-mediated Transport In Synapse
Pathways		Glucuronidation	Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Lipid traits (pleiotropy) (HIPO component 2) ( 30289880) Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102) Sex hormone-binding globulin levels ( 22829776) Urinary metabolite levels in chronic kidney disease ( 31959995)	Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 27863252)
Interacting Genes		1 interacting genes: RAB8A	34 interacting genes: ASNS BAG6 BIRC6 GDI2 IKBKG JAK3 KCNN1 MALT1 MAP4K2 MDM2 MYO5C MYO9B NR2F6 OCRL ODF2 OPTN PDE6D PQBP1 PRKACA RAB11A RAB13 RAB3IL1 RAB3IP RABIF RIMS2 RPH3A RPH3AL STEAP1 SYTL1 SYTL4 TAS2R9 TFRC TPM4 UGT2B15
Entrez ID		7366	4218
HPRD ID		07192	01296
Ensembl ID		ENSG00000196620	ENSG00000167461
Uniprot IDs		P54855	A0A024R7I3 P61006
PDB IDs			3QBT 3TNF 4LHV 4LHW 4LHX 4LHY 4LHZ 4LI0 5SZI
Enriched GO Terms of Interacting Partners?
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