SCGB1A1 and TRIM32

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		SCGB1A1	TRIM32
Description		secretoglobin family 1A member 1	tripartite motif containing 32
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nuclear Envelope Cytoplasm Rough Endoplasmic Reticulum Secretory Granule Extracellular Exosome	Cell Nucleus Cytoplasm Cytosol Striated Muscle Myosin Thick Filament
	Molecular Function	Protein Binding Phospholipase A2 Inhibitor Activity Polychlorinated Biphenyl Binding	Transcription Coactivator Activity RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Myosin Binding Tat Protein Binding Translation Initiation Factor Binding Identical Protein Binding Ubiquitin Binding Protein Self-association Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Female Pregnancy Embryo Implantation Response To Xenobiotic Stimulus Response To Ozone Response To Lipopolysaccharide Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-4 Production Negative Regulation Of Interleukin-5 Production Response To Silicon Dioxide Response To Cytokine Negative Regulation Of T Cell Proliferation Negative Regulation Of Catalytic Activity Regulation Of MRNA Stability Regulation Of Inflammatory Response Response To Glucocorticoid Response To Fibroblast Growth Factor	Protein Polyubiquitination Tissue Homeostasis Ubiquitin-dependent Protein Catabolic Process Actin Ubiquitination Response To UV Protein Ubiquitination Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Regulation Of Type I Interferon Production Negative Regulation Of Viral Transcription Response To Tumor Necrosis Factor Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Fat Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Muscle Cell Cellular Homeostasis Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Striated Muscle Cell Differentiation Axon Development Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Interleukin-17-mediated Signaling Pathway Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production Positive Regulation Of Cell Motility
Pathways			Regulation of innate immune responses to cytosolic DNA Antigen processing: Ubiquitination & Proteasome degradation
Drugs		4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL
Diseases			Bardet-Biedl syndrome (BBS)
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Gamma glutamyl transferase levels ( 29403010) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Estimated glomerular filtration rate ( 31015462)
Interacting Genes		6 interacting genes: CUBN FN1 LMBR1L LRP2 MARK2 TRIM32	41 interacting genes: ABI2 ATXN1 CLIP4 GLIS2 HSPA4 IQCB1 IRAK1 KCTD9 MID2 MYCN NDRG2 PDE9A PIAS3 PIAS4 PTCD2 PTPN11 RABAC1 RNF208 RNF41 SCGB1A1 SDCBP STING1 SYT6 TOP1 TRIM23 TRIM27 TRIM5 TRIM72 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN1 UBQLN4 VPS11 XIAP
Entrez ID		7356	22954
HPRD ID		01884	03797
Ensembl ID		ENSG00000149021	ENSG00000119401
Uniprot IDs		A0A0S2Z4R6 P11684	A0A024R843 Q13049
PDB IDs			2CT2 5FEY
Enriched GO Terms of Interacting Partners?
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