UCHL3 and LONRF1

Number of citations of the paper that reports this interaction (PubMedID 23105109)
16

Data Source:
BioGRID (two hybrid)

		UCHL3	LONRF1
Description		ubiquitin C-terminal hydrolase L3	LON peptidase N-terminal domain and ring finger 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Cytosol
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity NEDD8-specific Protease Activity Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding	Protein Binding Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Protein Catabolic Process Post-translational Protein Modification	Protein Polyubiquitination
Pathways		UCH proteinases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Neddylation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Diabetic retinopathy ( 23562823) Metabolite levels ( 23823483)	Colorectal cancer (diet interaction) ( 24743840)
Interacting Genes		19 interacting genes: ATM ATXN7L3 CDH1 LONRF1 NEDD8 NSG2 PJA1 PLA2G2A POGK RAD51 TRIM27 TRIM54 TRIM55 TRIM63 UBE2S USP15 USP21 USP28 XRCC5	33 interacting genes: ADAMTSL4 ALAS1 ATG9A BRCA1 BYSL CALCOCO2 CRX EFHC2 GORASP1 GORASP2 HSPB1 IHO1 IKZF2 IQCF2 KAT5 KCTD9 KRT31 KRTAP13-1 LHX4 NR4A1 NTAQ1 PLSCR1 RBPMS SFN SPRY2 STAU1 STX11 TRIM42 TRIM9 UBE2L6 UCHL3 USP2 XIAP
Entrez ID		7347	91694
HPRD ID		04367	08674
Ensembl ID		ENSG00000118939	ENSG00000154359
Uniprot IDs		A0A087WTB8 A0A140VJZ4 P15374	Q17RB8
PDB IDs		1UCH 1XD3 6ISU
Enriched GO Terms of Interacting Partners?
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