TTPA and CMTM5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TTPA	CMTM5
Description		alpha tocopherol transfer protein	CKLF like MARVEL transmembrane domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Cell Late Endosome Cytosol	Extracellular Space Integral Component Of Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Vitamin E Binding Phosphatidylinositol-3,4-bisphosphate Binding Intermembrane Lipid Transfer Activity Phosphatidylinositol Bisphosphate Binding	Cytokine Activity Protein Binding
	Biological Process	Embryonic Placenta Development Lipid Metabolic Process Response To Nutrient Response To PH Response To Toxic Substance Vitamin E Metabolic Process Vitamin Transport Intracellular PH Reduction Negative Regulation Of Cell Death Negative Regulation Of Establishment Of Blood-brain Barrier Intermembrane Lipid Transfer	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation
Pathways		Vitamin E
Drugs
Diseases		Ataxia with isolated vitamin E deficiency (AVED); Friedreich-like ataxia
GWAS
Interacting Genes		2 interacting genes: APP CMTM5	54 interacting genes: AACS ACSF2 ALDH18A1 APOA1 ARMC9 COQ8A CPLX1 CREB3 CYP1A1 DDA1 ECPAS FAM114A1 FARS2 FERMT2 GAD1 GAD2 GLTP GOLGA2P10 GTF3C1 HNRNPK LMNA LMO2 MCEE MTERF3 MYG1 NDRG4 PIMREG PITPNC1 PLIN3 PNPO PPIF PPP2R3C PTPN9 RBFA RMDN2 RNF185 RSRC2 SDCBP SH3GLB1 SHMT2 SNX1 SPATA8 SPG21 SSX3 SUCLA2 SYNE4 TIMM44 TPD52L3 TTPA TUBB TUFM VARS2 ZNF391 ZNF599
Entrez ID		7274	116173
HPRD ID		02685	06986
Ensembl ID		ENSG00000137561	ENSG00000166091
Uniprot IDs		P49638	Q96DZ9
PDB IDs		1OIP 1OIZ 1R5L 5MUE 5MUG
Enriched GO Terms of Interacting Partners?
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