TRPC5 and STMN2

Number of citations of the paper that reports this interaction (PubMedID 12858178)
102

Data Source:
HPRD (two hybrid, in vivo)

		TRPC5	STMN2
Description		transient receptor potential cation channel subfamily C member 5	stathmin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Dendrite Growth Cone Cation Channel Complex Calcium Channel Complex Neuronal Cell Body Membrane Raft	Cytoplasm Endosome Golgi Apparatus Membrane Lamellipodium Growth Cone Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Clathrin Binding Actinin Binding ATPase Binding Inositol 1,4,5 Trisphosphate Binding	Protein Binding Tubulin Binding Calcium-dependent Protein Binding
	Biological Process	Calcium Ion Transport Manganese Ion Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Nervous System Development Positive Regulation Of Cell Proliferation Positive Regulation Of Peptidyl-threonine Phosphorylation Neuron Differentiation Positive Regulation Of Axon Extension Negative Regulation Of Dendrite Morphogenesis Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport Regulation Of Membrane Hyperpolarization	Microtubule Depolymerization Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Depolymerization Neuron Projection Development Regulation Of Cytoskeleton Organization Cellular Response To Nerve Growth Factor Stimulus
Pathways		TRP channels Role of second messengers in netrin-1 signaling
Drugs
Diseases
GWAS		Smoking behavior ( 19247474)	Creutzfeldt-Jakob disease ( 19081515) Frontotemporal dementia with GRN mutation (age at onset) ( 29724592) Metabolite levels ( 23823483) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)
Interacting Genes		9 interacting genes: DRD2 ENKUR ITPR3 MX1 SLC9A3R1 STMN2 STMN3 TRPC1 TRPC4	19 interacting genes: CCDC85A CDK1 CEP70 EEF1A1 FANCC GPRASP1 GPRASP2 MAPK10 MAPK3 NGFR PRKACA PSMC1 RGS20 RGS6 TEX11 TFCP2 TRPC5 TXLNA UBE2I
Entrez ID		7224	11075
HPRD ID		02273	09003
Ensembl ID		ENSG00000072315	ENSG00000104435
Uniprot IDs		Q9UL62	Q93045
PDB IDs
Enriched GO Terms of Interacting Partners?
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