TPP2 and EHHADH

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TPP2	EHHADH
Description		tripeptidyl peptidase 2	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Nuclear Body	Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Endopeptidase Activity Aminopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Tripeptidyl-peptidase Activity Identical Protein Binding	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Enzyme Binding
	Biological Process	Protein Polyubiquitination Proteolysis	Internal Protein Amino Acid Acetylation Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import
Drugs			NADH
Diseases
GWAS			Cognitive performance ( 19734545) Major depressive disorder ( 27519822 21042317)
Interacting Genes		4 interacting genes: EHHADH MTNR1A POLB PPP1R16A	27 interacting genes: ACTB ACTG1 BHLHE40 CAT CBS CCDC102B DES FUNDC1 KCTD6 KCTD9 KRTAP10-7 LZTS2 MID1 NECAB2 PNMA1 SCP2 SSNA1 SSX2IP TNIP1 TPP2 TRAF1 TRIM27 TRIM41 TRIM54 TRIM55 TRIM63 ZBTB9
Entrez ID		7174	1962
HPRD ID		01834	06125
Ensembl ID		ENSG00000134900	ENSG00000113790
Uniprot IDs		P29144 Q5VZU9	Q08426
PDB IDs
Enriched GO Terms of Interacting Partners?
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