TNR and CCDC146

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TNR	CCDC146
Description		tenascin R	coiled-coil domain containing 146
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Surface Membrane Raft Perineuronal Net Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Cytoplasm Centriole
	Molecular Function		Protein Binding
	Biological Process	Cell Adhesion Neuron Cell-cell Adhesion Axon Guidance Associative Learning Telencephalon Cell Migration Negative Regulation Of Cell-cell Adhesion Extracellular Matrix Organization Locomotory Exploration Behavior Negative Regulation Of Axon Extension Involved In Regeneration Negative Regulation Of Synaptic Transmission Synapse Organization Neuromuscular Process Controlling Balance Positive Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Transmission Of Nerve Impulse Long-term Synaptic Potentiation
Pathways		ECM proteoglycans
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Attention deficit hyperactivity disorder ( 30563984) Body mass index ( 26426971) Corneal astigmatism ( 29422769) Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644) Liver fibrosis in non-alcoholic fatty acid liver disease ( 31311600) Telomere length ( 30185882) Tonometry ( 17903302)	Body mass index ( 28892062) Response to amphetamines ( 22952603)
Interacting Genes		15 interacting genes: ACAN BCAN CCDC146 CNTN1 LGALS14 MAGEB4 NCAN NCK2 NFASC NTAQ1 POLR3C PSMA1 PTPRZ1 SIGLEC1 VCAN	33 interacting genes: CBY2 CCDC136 CCNDBP1 CEP170P1 CEP44 DTNBP1 GOLGA2 KRT18 KRT19 KRT38 KRT40 MAGEA11 MAGEA6 MED4 MTUS2 NECAB2 NINL NUP62 PDE4DIP PNMA1 PSMC6 RINT1 RNF40 RPGRIP1 TFIP11 TNR TPM3 TRAF1 TRIM23 TRIM54 TSC22D4 USHBP1 VPS52
Entrez ID		7143	57639
HPRD ID		03589	11150
Ensembl ID		ENSG00000116147	ENSG00000135205
Uniprot IDs		A1L306 Q92752	Q8IYE0 Q96MS1
PDB IDs
Enriched GO Terms of Interacting Partners?
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