TNFRSF1B and CSNK1A1L

Number of citations of the paper that reports this interaction (PubMedID 8051045)
1

Data Source:
BioGRID (enzymatic study)

		TNFRSF1B	CSNK1A1L
Description		TNF receptor superfamily member 1B	casein kinase 1 alpha 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Tumor Necrosis Factor Receptor Superfamily Complex Extracellular Region Nucleus Plasma Membrane Membrane Integral Component Of Membrane Specific Granule Membrane Neuronal Cell Body Varicosity Membrane Raft Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Cytosol
	Molecular Function	Tumor Necrosis Factor-activated Receptor Activity Protein Binding Ubiquitin Protein Ligase Binding Tumor Necrosis Factor Binding	Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Regulation Of T Cell Cytokine Production Regulation Of Cytokine Secretion Involved In Immune Response Aortic Valve Development Pulmonary Valve Development Negative Regulation Of Extracellular Matrix Constituent Secretion Inflammatory Response Aging Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Cardiac Muscle Hypertrophy Cytokine-mediated Signaling Pathway Regulation Of Myelination Positive Regulation Of Myelination Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of T Cell Proliferation Neutrophil Degranulation Positive Regulation Of Oligodendrocyte Differentiation RNA Destabilization Positive Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of Cell Death Cellular Response To Lipopolysaccharide Cellular Response To Growth Factor Stimulus Extrinsic Apoptotic Signaling Pathway Regulation Of Neuroinflammatory Response Negative Regulation Of Neuroinflammatory Response Negative Regulation Of Neuron Death Positive Regulation Of Apoptotic Process Involved In Morphogenesis Regulation Of RNA Biosynthetic Process	Wnt Signaling Pathway Peptidyl-serine Phosphorylation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		TNFR2 non-canonical NF-kB pathway TNFs bind their physiological receptors Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling Neutrophil degranulation
Drugs		Etanercept
Diseases		Graft-versus-host disease
GWAS		Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058) Tuberculosis ( 29036319) Urate levels (BMI interaction) ( 25811787)	Adiponectin levels in pregnancy ( 28317342) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Palmitoleic acid (16:1n-7) levels ( 23362303)
Interacting Genes		21 interacting genes: ADAM17 BMX CAV1 CD14 CSNK1A1 CSNK1A1L FANCD2 HIVEP3 KRT18 LTA PKN1 STAT1 TDP2 TNF TRAF1 TRAF2 TRAF3 TRAIP TRIM37 UBQLN1 ZNF420	5 interacting genes: CEACAM3 CEBPE JAM2 TNFRSF1A TNFRSF1B
Entrez ID		7133	122011
HPRD ID		01862	13095
Ensembl ID		ENSG00000028137	ENSG00000180138
Uniprot IDs		P20333	Q8N752
PDB IDs		1CA9 3ALQ
Enriched GO Terms of Interacting Partners?
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