TJP1 and YBX3

Number of citations of the paper that reports this interaction (PubMedID 16508013)
78

Data Source:
BioGRID (pull down)

		TJP1	YBX3
Description		tight junction protein 1	Y-box binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Cytoplasm Cytosol Plasma Membrane Adherens Junction Gap Junction Bicellular Tight Junction Basolateral Plasma Membrane Cell Junction Protein-containing Complex Cell Projection Apical Junction Complex Apical Part Of Cell Tight Junction	Nucleus Cytoplasm Cytosol Bicellular Tight Junction Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Calmodulin Binding Cadherin Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nucleic Acid Binding Double-stranded DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Rho GTPase Binding Polysome Binding
	Biological Process	Cell-cell Junction Assembly Positive Regulation Of Cell Migration Actomyosin Structure Organization Adherens Junction Maintenance Hippo Signaling Cell-cell Junction Organization Regulation Of Cytoskeleton Organization Negative Regulation Of Stress Fiber Assembly Protein Localization To Adherens Junction Establishment Of Endothelial Intestinal Barrier Regulation Of Cell Junction Assembly Protein Localization To Bicellular Tight Junction Positive Regulation Of Sprouting Angiogenesis Positive Regulation Of Maintenance Of Permeability Of Blood-brain Barrier Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Negative Regulation Of Actin Cytoskeleton Reorganization Regulation Of Bicellular Tight Junction Assembly	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Spermatogenesis Male Gonad Development Response To Cold Fertilization Regulation Of Gene Expression Positive Regulation Of Organ Growth Negative Regulation Of Skeletal Muscle Tissue Development Negative Regulation Of Necroptotic Process 3'-UTR-mediated MRNA Stabilization Cellular Response To Tumor Necrosis Factor Cellular Hyperosmotic Response Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Positive Regulation Of Cytoplasmic Translation
Pathways		Regulation of gap junction activity Regulation of gap junction activity Signaling by Hippo Apoptotic cleavage of cell adhesion proteins RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS		Central corneal thickness ( 31798171 29760442 30894546) Corneal structure ( 23291589) Response to antipsychotic treatment ( 23241943)
Interacting Genes		40 interacting genes: ACTA1 ACTN4 AFDN ARVCF CGN CLDN1 CLDN16 CLDN2 CLDN3 CLDN4 CLDN5 CLDN6 CLDN7 CLDN8 CNKSR2 CTNNA1 CTTN EGFR F11R GJA1 GJA3 GJA8 GJB3 GJC1 GJD3 GRIN1 GRIN2D HSP90AA1 JAM2 JAM3 KHDRBS1 KIRREL1 OCLN PEA15 PTPN14 TJP2 TJP3 TRPC4 UBN1 YBX3	12 interacting genes: CDK4 CDK5 GSK3B IL7R MAPK1 NFYB PCBP2 RALA SRPK2 SYMPK TJP1 VEGFA
Entrez ID		7082	8531
HPRD ID		03002	10347
Ensembl ID		ENSG00000104067	ENSG00000060138
Uniprot IDs		A9CQZ8 B4DZK4 G3V1L9 G5E9E7 Q07157 Q6MZU1	A0A024RAQ1 A0A024RAV4 P16989
PDB IDs		2H2B 2H2C 2H3M 2JWE 2KXR 2KXS 2RCZ 3CYY 3LH5 3SHU 3SHW 3TSV 3TSW 3TSZ 4OEO 4OEP 4Q2Q 4YYX
Enriched GO Terms of Interacting Partners?
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