TFF1 and SIGLEC8

Number of citations of the paper that reports this interaction (PubMedID 21982860)
16

		TFF1	SIGLEC8
Description		trefoil factor 1	sialic acid binding Ig like lectin 8
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Growth Factor Activity	Transmembrane Signaling Receptor Activity Protein Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Carbohydrate Metabolic Process Signal Transduction Negative Regulation Of Cell Proliferation Response To Iron Ion Cell Differentiation Maintenance Of Gastrointestinal Epithelium Response To Immobilization Stress Response To Peptide Hormone	Cell Adhesion Signal Transduction
Pathways		Estrogen-dependent gene expression	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Raloxifene Afimoxifene
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Pancreatic cancer ( 22158540)
Interacting Genes		18 interacting genes: AKT1 APC ATM BTN3A1 BTNL8 CD300LD ESR2 FCRL4 FGFR2 GKN2 MUC6 RAD51 SIGLEC8 TSG101 UBQLN1 UBQLN4 XRCC3 ZNF250	1 interacting genes: TFF1
Entrez ID		7031	27181
HPRD ID		00219	16132
Ensembl ID		ENSG00000160182	ENSG00000105366
Uniprot IDs		P04155	Q9NYZ4
PDB IDs		1HI7 1PS2	2N7A 2N7B
Enriched GO Terms of Interacting Partners?
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