TCP10L3 and CEP43

		TCP10L3	CEP43
Description		t-complex 10 like 3, pseudogene	centrosomal protein 43
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Centriole Cytosol	Nucleus Centrosome Centriole Cytosol Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Corepressor Activity	Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Inhibitor Activity Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Nucleic Acid-templated Transcription	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Kinase Activity Positive Regulation Of Cell Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Microtubule Anchoring Negative Regulation Of Protein Tyrosine Kinase Activity Ciliary Basal Body-plasma Membrane Docking
Pathways			Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Signaling by FGFR1 in disease AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: APP CEP43 FBXO7 PARD6A PARD6B UBC	8 interacting genes: LINC01558 NAGK PPP2R1B RNASET2 S100A6 TBP TCP10L3 VASP
Entrez ID		6953	11116
HPRD ID		01752	10392
Ensembl ID			ENSG00000213066
Uniprot IDs			A0A087WV25 B4DH64 O95684
PDB IDs			2D68
Enriched GO Terms of Interacting Partners?
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