ELOC and CPTP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ELOC	CPTP
Description		elongin C	ceramide-1-phosphate transfer protein
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Elongin Complex	Nuclear Outer Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Membrane
	Molecular Function	Protein Binding	Phospholipid Binding Lipid Binding Ceramide 1-phosphate Binding Ceramide 1-phosphate Transporter Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Ubiquitin-dependent Protein Catabolic Process Viral Process Protein Ubiquitination Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Post-translational Protein Modification Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia	Glycosphingolipid Metabolic Process Negative Regulation Of Autophagy Ceramide Transport Glycolipid Transport Negative Regulation Of Interleukin-1 Beta Secretion Intermembrane Lipid Transfer Negative Regulation Of NLRP3 Inflammasome Complex Assembly Ceramide 1-phosphate Transport
Pathways		Formation of RNA Pol II elongation complex Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Vif-mediated degradation of APOBEC3G RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation Neddylation Regulation of expression of SLITs and ROBOs Antigen processing: Ubiquitination & Proteasome degradation	Glycosphingolipid metabolism
Drugs
Diseases
GWAS
Interacting Genes		47 interacting genes: CBX5 CENPC COMMD1 CPTP CUL2 CUL3 CYP2J2 ECT2 EFNB3 ELOA2 ELOA3 ELOB EPOR GDAP1 GHR HNF4G ID2 INSIG1 JTB KRT8 LRRC41 LY96 MCM7 MED8 METTL21C MRAS NAA25 NFKBIA NOTCH4 NRCAM PEX2 PRAME RCAN2 RNF7 RPL7 SAT2 SERTAD1 SKAP1 SOCS1 SOCS3 SOCS6 UBC UBE2W USP33 VHL WNT7B ZYG11B	7 interacting genes: CD7 ECM1 ELOC INPP5K PHF13 SMAD3 ZNF451
Entrez ID		6921	80772
HPRD ID		02875	18878
Ensembl ID		ENSG00000154582	ENSG00000224051
Uniprot IDs		A0A024R7Y5 Q15369	Q5TA50 S4S694
PDB IDs		1LM8 1LQB 1VCB 2C9W 2IZV 2MA9 3DCG 3ZKJ 3ZNG 3ZRC 3ZRF 3ZTC 3ZTD 3ZUN 4AJY 4AWJ 4B95 4B9K 4BKS 4BKT 4N9F 4W9C 4W9D 4W9E 4W9F 4W9G 4W9H 4W9I 4W9J 4W9K 4W9L 4WQO 5BO4 5LLI 5N4W 5NVV 5NVW 5NVX 5NVY 5NVZ 5NW0 5NW1 5NW2 5T35 6BVB 6C5X 6FMI 6FMJ 6FMK 6GFX 6GFY 6GFZ 6GMN 6GMQ 6GMR 6GMX 6HAX 6HAY 6HR2 6I4X 6I5J 6I5N 6I7R 6R7F 6R7H 6R7N	4K80 4K84 4K85 4K8N 4KBS 4KF6
Enriched GO Terms of Interacting Partners?
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