TAPBP and COPG2

Number of citations of the paper that reports this interaction (PubMedID 11884415)
14

Data Source:
HPRD (in vivo)

		TAPBP	COPG2
Description		TAP binding protein	COPI coat complex subunit gamma 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane MHC Class I Peptide Loading Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane COPI Vesicle Coat Transport Vesicle Growth Cone
	Molecular Function	Protein Binding Peptide Antigen-transporting ATPase Activity MHC Class I Protein Binding Peptide Antigen Binding TAP1 Binding TAP2 Binding Unfolded Protein Binding TAP Complex Binding	Structural Molecule Activity
	Biological Process	MHC Class Ib Protein Complex Assembly Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Retrograde Vesicle-mediated Transport, Golgi To ER Immune Response Regulation Of Gene Expression Peptide Transport Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Peptide Antigen Stabilization Regulation Of Protein Complex Stability Protein-containing Complex Assembly Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Protein Secretion Organelle Transport Along Microtubule
Pathways		ER-Phagosome pathway Antigen Presentation: Folding, assembly and peptide loading of class I MHC	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases		Bare lymphocyte syndrome (BLS) type1
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576 29875488)	Pancreatic cancer ( 25086665) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		9 interacting genes: CALR COPB1 COPG1 COPG2 HLA-A HLA-C TAP1 TAP2 UBC	12 interacting genes: ARCN1 ARL1 COPB1 COPE COPG1 COPZ1 COPZ2 DRD1 HES4 PTGES3 TAPBP TMED10
Entrez ID		6892	26958
HPRD ID		09061	05074
Ensembl ID		ENSG00000231925	ENSG00000158623
Uniprot IDs		A0A024RCT1 A0A0A0MSV9 A0A0A0MT98 O15533	A0A140VK12 Q9NSM7 Q9UBF2
PDB IDs		3F8U 6ENY
Enriched GO Terms of Interacting Partners?
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