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KLF5 and GTF2F2
Number of citations of the paper that reports this interaction (PubMedID
9089417
)
7
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
KLF5
GTF2F2
Description
Kruppel like factor 5
general transcription factor IIF subunit 2
Image
GO Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Nucleoplasm
Transcription Factor Complex
Golgi Apparatus
Intracellular Membrane-bounded Organelle
Nucleus
Nucleoplasm
Transcription Factor TFIIF Complex
Microtubule Cytoskeleton
Transcriptional Preinitiation Complex
Molecular Function
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
MRF Binding
Metal Ion Binding
DNA Binding
DNA Helicase Activity
Protein Binding
ATP Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Angiogenesis
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Positive Regulation Of Cell Proliferation
Skeletal Muscle Satellite Cell Differentiation
Satellite Cell Activation Involved In Skeletal Muscle Regeneration
Myotube Differentiation Involved In Skeletal Muscle Regeneration
Microvillus Assembly
Regulation Of Microvillus Assembly
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Intestinal Epithelial Cell Development
Positive Regulation Of Transcription By Transcription Factor Localization
Cellular Response To Organic Cyclic Compound
Cell-cell Signaling Via Exosome
Cellular Response To Peptide
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Cellular Response To Leukemia Inhibitory Factor
MRNA Splicing, Via Spliceosome
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Fibroblast Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
DNA Duplex Unwinding
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Viral Transcription
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Pathways
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of granulopoiesis
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
29679657
)
Blood urea nitrogen levels (
31152163
)
Breast cancer (
27117709
)
Breast cancer (estrogen-receptor negative) (
27117709
29058716
)
Breast Cancer in BRCA1 mutation carriers (
29058716
)
Chronotype (
30696823
)
Colorectal cancer (
30529582
)
Colorectal cancer or advanced adenoma (
30510241
)
Creatine kinase levels (
29403010
)
Endometrial cancer (
30093612
27008869
)
Endometrial cancer (endometrioid histology) (
30093612
)
Intraocular pressure (
29785010
31959993
)
Pancreatic cancer (
29422604
20101243
26098869
25086665
)
Prostate cancer (
31562322
26443449
)
Systolic blood pressure (
30224653
)
Type 2 diabetes (
25760438
)
Normal facial asymmetry (angle of surface orientation score) (
30631343
)
Type 2 diabetes (
25760438
)
Interacting Genes
27 interacting genes:
ANP32B
ATXN3L
BAP1
CREBBP
EP300
ESR1
FBXW7
GSK3B
GTF2B
GTF2E2
GTF2F2
HDAC1
JUN
NCOR1
NCOR2
NFKB1
PARP1
PPARG
PRKCA
PRKCD
RARA
RXRA
SET
SMURF2
TBP
UBE2I
WWP1
30 interacting genes:
AHR
AR
ARNT
ATF2
ATF4
CEBPG
CREB1
FOS
GTF2B
GTF2E1
GTF2E2
GTF2F1
HMGA1
HTATSF1
JUN
KLF5
MSX2
MYC
POLR2A
POLR2E
RBPMS
RPL27A
TAF5
TBP
TCEA1
TCTEX1D2
TRAM2
TSC22D1
TSPAN3
URI1
Entrez ID
688
2963
HPRD ID
04212
01804
Ensembl ID
ENSG00000102554
ENSG00000188342
Uniprot IDs
Q13887
Q5T6X2
A0A024RDU9
P13984
PDB IDs
2EBT
1BBY
1F3U
2BBY
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6O9L
Enriched GO Terms of Interacting Partners
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