SUPT6H and HSPA9

Number of citations of the paper that reports this interaction (PubMedID 19299420)
12

Data Source:
BioGRID (pull down)

		SUPT6H	HSPA9
Description		SPT6 homolog, histone chaperone and transcription elongation factor	heat shock protein family A (Hsp70) member 9
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Elongation Factor Complex Transcriptionally Active Chromatin	Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Focal Adhesion Mitochondrial Nucleoid Extracellular Exosome
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Nucleosome Binding Histone Binding	RNA Binding Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding ATPase Activity, Coupled Protein Binding Involved In Protein Folding Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Blastocyst Formation Chromatin Remodeling Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Nucleosome Organization MRNA Transcription By RNA Polymerase II Regulation Of Isotype Switching Regulation Of MRNA Processing MRNA Transport Regulation Of Muscle Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation Chromatin Maintenance	Protein Export From Nucleus Response To Unfolded Protein Iron-sulfur Cluster Assembly Erythrocyte Differentiation Cellular Response To Unfolded Protein Interleukin-12-mediated Signaling Pathway Protein Refolding Negative Regulation Of Apoptotic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	Mitochondrial protein import Regulation of HSF1-mediated heat shock response Cristae formation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Pulse pressure ( 30578418)	Autism spectrum disorder or schizophrenia ( 28540026) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061 29483656)
Interacting Genes		9 interacting genes: AKT1 CSNK2A1 ERBB2 HSP90B1 HSPA9 HSPD1 IWS1 MCPH1 TSC2	22 interacting genes: APP DNAJC19 DNLZ FGF1 HSP90B1 HSPBP1 LSM8 MATK MVD NELFB PTPN11 PTPRF SIRPA STUB1 SUMO2 SUMO4 SUPT6H TIMM44 TP53 XPO1 YKT6 YWHAG
Entrez ID		6830	3313
HPRD ID		03211	02770
Ensembl ID		ENSG00000109111	ENSG00000113013
Uniprot IDs		Q7KZ85	A0A384P5G6 P38646
PDB IDs		6GME 6GMH	3N8E 4KBO 6NHK 6P2U
Enriched GO Terms of Interacting Partners?
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