SNX2 and SNX4

Number of citations of the paper that reports this interaction (PubMedID 9819414)
78

Data Source:
HPRD (in vitro, in vivo)

		SNX2	SNX4
Description		sorting nexin 2	sorting nexin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Protein-containing Complex	Cytoplasm Cytoplasmic Dynein Complex Plasma Membrane Membrane SNARE Complex Early Endosome Membrane Protein-containing Complex
	Molecular Function	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Intracellular Protein Transport Endocytosis Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Lamellipodium Morphogenesis	Protein Transport Endocytic Recycling Positive Regulation Of Histamine Secretion By Mast Cell
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308)	Estimated glomerular filtration rate in non-diabetics ( 31451708) Urate levels ( 31578528)
Interacting Genes		20 interacting genes: ACVR1B ACVR2B C1orf122 CSNK2B DUSP10 EGFR FNBP1 INSR LAMC1 LEPR MET NFYC PAK6 PDGFRA PDGFRB SNX1 SNX4 SNX5 SNX6 ZNF202	15 interacting genes: AGK ARL6IP1 ATP6V0A1 BIN1 EGFR HIVEP1 INSR LEPR MAGEA6 PDGFRA PDGFRB PTPN5 SNX2 SNX6 SUPT5H
Entrez ID		6643	8723
HPRD ID		09332	09334
Ensembl ID		ENSG00000205302	ENSG00000114520
Uniprot IDs		O60749	O95219
PDB IDs
Enriched GO Terms of Interacting Partners?
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