STK33 and USP15

Number of citations of the paper that reports this interaction (PubMedID 22451720)
25

Data Source:
BioGRID (pull down)

		STK33	USP15
Description		serine/threonine kinase 33	ubiquitin specific peptidase 15
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Transforming Growth Factor Beta Receptor Binding Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Identical Protein Binding SMAD Binding Ubiquitin Modification-dependent Histone Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Protein Autophosphorylation	Ubiquitin-dependent Protein Catabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Viral Process Protein Deubiquitination BMP Signaling Pathway Monoubiquitinated Protein Deubiquitination Histone H2B Conserved C-terminal Lysine Deubiquitination Pathway-restricted SMAD Protein Phosphorylation Protein K48-linked Deubiquitination Positive Regulation Of RIG-I Signaling Pathway
Pathways			Downregulation of TGF-beta receptor signaling UCH proteinases Ub-specific processing proteases
Drugs
Diseases
GWAS		Body mass index ( 26426971 19079261 28892062 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Intake of total sugars ( 31005972) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Small cell lung carcinoma ( 28604730)	Alopecia areata ( 25608926) Metabolite levels ( 23823483) Plateletcrit ( 27863252) Pulmonary function decline ( 22424883) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271)
Interacting Genes		4 interacting genes: APP GLYCTK USP15 USP5	47 interacting genes: BAP1 BMPR1A BRAP CARD9 CCDC57 DDX58 FHL1 H2BC21 JOSD1 KEAP1 MAD1L1 MDC1 MDM2 OTUB1 PHF7 PLA2G2A PRPF31 RBCK1 RNF126 RNF144B SENP3 SENP8 SMURF2 SPDL1 STAM STK33 TRAF6 TRIM17 TRIM21 TRIM25 TRIM46 TRIM5 TRIM54 TRIM63 TRIM74 UBC UBE2S UCHL1 UCHL3 USP14 USP20 USP21 USP28 USP33 USP51 USP8 YOD1
Entrez ID		65975	9958
HPRD ID		09642	05293
Ensembl ID		ENSG00000130413	ENSG00000135655
Uniprot IDs		B3KS39 B4DDH2 F8WAK5 Q9BYT3	Q9Y4E8
PDB IDs			1W6V 3LMN 3PPA 3PV1 3T9L 4A3O 4A3P 5JJW 6CPM 6CRN 6DJ9 6GH9 6GHA 6ML1
Enriched GO Terms of Interacting Partners?
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