SLCO1A2 and PDZK1

Number of citations of the paper that reports this interaction (PubMedID 15553237)
12

Data Source:
HPRD (two hybrid)

		SLCO1A2	PDZK1
Description		solute carrier organic anion transporter family member 1A2	PDZ domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Brush Border Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Organic Anion Transmembrane Transporter Activity Bile Acid Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity	Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-containing Complex Binding
	Biological Process	Organic Anion Transport Bile Acid And Bile Salt Transport Sodium-independent Organic Anion Transport Transmembrane Transport	Carnitine Transport Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Anion Transport Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Drug Transmembrane Export
Pathways		Recycling of bile acids and salts Transport of organic anions
Drugs		Rifampicin
Diseases
GWAS		AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875) Bilirubin levels ( 19414484) Diisocyanate-induced asthma ( 25918132) Methotrexate phramacokinetics (acute lymphoblastic leukemia) ( 19901119) Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Progressive supranuclear palsy ( 30089514 21685912) Serum metabolite levels ( 23093944) Statin-induced myopathy (severe) ( 31220337)	Contrast sensitivity ( 24152035) Serum uric acid levels ( 30993211) Urate levels ( 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)
Interacting Genes		4 interacting genes: PDZD3 PDZK1 SLC9A3R1 SLC9A3R2	29 interacting genes: ABCA1 ABCC2 ABCC4 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I
Entrez ID		6579	5174
HPRD ID		09112	04829
Ensembl ID		ENSG00000084453	ENSG00000174827
Uniprot IDs		A0A024RAT5 P46721	Q5T2W1
PDB IDs			2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI
Enriched GO Terms of Interacting Partners?
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