SLC3A1 and SLC7A8

Number of citations of the paper that reports this interaction (PubMedID 10574970)
65

Data Source:
HPRD (in vivo)

		SLC3A1	SLC7A8
Description		solute carrier family 3 member 1	solute carrier family 7 member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Vacuolar Membrane Plasma Membrane Integral Component Of Plasma Membrane Membrane Brush Border Membrane Extracellular Exosome	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	Catalytic Activity Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity Protein-containing Complex Binding	Protein Binding Organic Cation Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity Peptide Antigen Binding
	Biological Process	Carbohydrate Metabolic Process Amino Acid Transport Basic Amino Acid Transport L-cystine Transport Basic Amino Acid Transmembrane Transport	Amino Acid Transmembrane Transport Amino Acid Transport Response To Toxic Substance Organic Cation Transport Neutral Amino Acid Transport Leukocyte Migration Metal Ion Homeostasis Toxin Transport L-alpha-amino Acid Transmembrane Transport
Pathways		Amino acid transport across the plasma membrane Defective SLC3A1 causes cystinuria (CSNU) Defective SLC7A9 causes cystinuria (CSNU)	Basigin interactions Amino acid transport across the plasma membrane
Drugs		Cystine	L-Phenylalanine L-Alanine
Diseases		Cystinuria
GWAS		antipsychotic drug dosage in schizophrenia or schizoaffective disorder ( 26821981)
Interacting Genes		2 interacting genes: NPTX1 SLC7A8	2 interacting genes: SLC3A1 SLC3A2
Entrez ID		6519	23428
HPRD ID		00090	11971
Ensembl ID		ENSG00000138079	ENSG00000092068
Uniprot IDs		A0A0S2Z4E1 B8ZZK1 Q07837	Q53EM9 Q9UHI5
PDB IDs
Enriched GO Terms of Interacting Partners?
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