MRPL44 and NGEF

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		MRPL44	NGEF
Description		mitochondrial ribosomal protein L44	neuronal guanine nucleotide exchange factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Plasma Membrane	Cytosol Membrane Growth Cone
	Molecular Function	RNA Binding Double-stranded RNA Binding Ribonuclease III Activity Protein Binding	Guanyl-nucleotide Exchange Factor Activity
	Biological Process	RNA Processing Production Of SiRNA Involved In RNA Interference Primary MiRNA Processing Pre-miRNA Processing Mitochondrial Translational Elongation Mitochondrial Translational Termination RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Dendritic Spine Morphogenesis
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	NRAGE signals death through JNK Rho GTPase cycle EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse G alpha (12/13) signalling events
Drugs
Diseases
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Contrast sensitivity ( 24152035) Heel bone mineral density ( 30598549 28869591) Pursuit maintenance gain ( 29064472) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Sudden cardiac arrest ( 30169657) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		15 interacting genes: ABI2 CEP70 DGKE IMMT ITFG1 NGEF PI4KA PLPP2 PTN SEMA5B SETDB1 SHC1 USP22 VIM ZNF235	10 interacting genes: ATP5F1C C7orf25 C8orf33 EPHA4 FAM118B HCK MRPL44 NUDT21 SH2D1A TAF1D
Entrez ID		65080	25791
HPRD ID		14763	10442
Ensembl ID		ENSG00000135900	ENSG00000066248
Uniprot IDs		A1MA90 Q9H9J2	B4DDI2 Q8N5V2
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
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